The Digestive Disease National Coalition (DDNC) is an advocacy organization comprised of the major national voluntary and professional societies concerned with digestive diseases. The DDNC focuses on improving public policy related to digestive diseases and increasing public awareness with respect to the many diseases of the digestive system. The DDNC was founded in 1978 and is based in Washington, D.C.

The Gastro-Intestinal Research Foundation (GIRF) is a not-for-profit organization dedicated to raising funds for clinical and laboratory research in digestive diseases in the Gastroenterology Section at the University of Chicago Medical Center.

The IFFGD is a nonprofit education and research organization dedicated to informing, assisting, and supporting people affected by gastrointestinal (GI) disorders. Founded in 1991, the IFFGD works with patients, families, physicians, nurses, practitioners, investigators, regulators, employers, and others to improve digestive health in adults and children.

The NDDIC is an information dissemination service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK is part of the National Institutes of Health (NIH), which is part of the U.S. Department of Health and Human Services.
NDDIC was established in 1980 to increase knowledge and understanding about digestive diseases among people with these conditions and their families, healthcare professionals, and the general public. To carry out this mission, NDDIC works closely with a coordinating panel of representatives from federal agencies, voluntary organizations on the national level, and professional groups to identify and respond to informational needs about digestive diseases.